Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783588 | 1.00 | TSHR (0.56) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL30953145 | 0.89 | TSHR (0.58) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL1626066 | 0.89 | TSHR (0.58) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL9180125 | 0.88 | TSHR (0.62) | TSHRMAPK1TDP1ALDH1A1GPR35 | |
| SCHEMBL14578462 | 0.83 | TDP1 (0.52) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL305109 | 0.83 | ALDH1A1 (0.55) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL3897956 | 0.83 | PDE7A (0.53) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL10400092 | 0.83 | TSHR (0.47) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL11619612 | 0.83 | TSHR (0.47) | TSHRMAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL3175084 | 0.83 | TSHR (0.48) | TSHRMAPK1TDP1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773207-A | Method and catalyst for selective nitro reduction hydrogenation reaction by using micro packed bed | 南京药石科技股份有限公司 | 2022-07-22 | — | — | CN | claimed |
| EP-1016405-A2 | Arylating medicaments | Radopath Pharmaceuticals International Limited (GB) | 2000-07-05 | — | — | EP | claimed |
| CN-1124012-A | Arylating medicaments | RADOPATH LTD (GB) | 1996-06-05 | — | — | CN | claimed |
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | claimed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | claimed |
| CN-114773207-A | Method and catalyst for selective nitro reduction hydrogenation reaction by using micro packed bed | 南京药石科技股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-111116372-B | 3,4 dichloronitrobenzene full-continuous flow synthesis process under action of catalyst | 浙江本立科技股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-211921383-U | 3, 4-dichloronitrobenzene integrated full-continuous flow reaction system | 浙江本立科技股份有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-111116372-A | 3,4 dichloronitrobenzene full-continuous flow synthesis process under action of catalyst | 浙江本立科技股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-1411993-B1 | RADIOLABELED IRREVERSIBLE INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE AND THEIR USE IN RADIOIMAGING AND RADIOTHERAPY | YISSUM RES DEV CO (IL) | 2010-05-05 | — | — | EP | disclosed |
| EP-1594504-A4 | NOVEL IRREVERSIBLE INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE AND USES THEREOF FOR THERAPY AND DIAGNOSIS | T K SIGNAL LTD (IL) | 2008-12-17 | — | — | EP | disclosed |
| EP-1411993-A4 | RADIOLABELED IRREVERSIBLE INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE AND THEIR USE IN RADIOIMAGING AND RADIOTHERAPY | YISSUM RES DEV CO (IL) | 2007-08-01 | — | — | EP | disclosed |
| US-5219938-A | Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0325892-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED PRIMARY AMINES | CIBA-GEIGY AG (CH) | 1993-02-03 | — | — | EP | disclosed |
| US-5128416-A | Automobile tire treads | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0473552-A1 | Process for the preparation of halogenated aromatic primary amines | CIBA-GEIGY AG (CH) | 1992-03-04 | — | — | EP | disclosed |
| US-5015692-A | Rubbers for tires having impact strength | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-14 | — | — | US | disclosed |
| US-4960936-A | Process for the preparation of halogenated aromatic primary amines | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4957976-A | IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0325892-A2 | Process for the preparation of halogenated primary amines | CIBA-GEIGY AG (CH) | 1989-08-02 | — | — | EP | disclosed |