Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241799 | 1.00 | METTL3 (0.54) | METTL3MAPTTP53CFDP2RX7 | |
| SCHEMBL3232549 | 0.91 | METTL3 (0.63) | METTL3MAPTTP53CFDLMNA | |
| SCHEMBL3239834 | 0.91 | METTL3 (0.49) | METTL3MAPTTP53CFDLMNA | |
| SCHEMBL3241266 | 0.90 | METTL3 (0.49) | METTL3MAPTTP53CFDLMNA | |
| SCHEMBL3239818 | 0.90 | METTL3 (0.49) | METTL3MAPTTP53CFDLMNA | |
| SCHEMBL3243216 | 0.89 | METTL3 (0.54) | METTL3MAPTTP53CFDLMNA | |
| SCHEMBL3239826 | 0.89 | METTL3 (0.50) | METTL3MAPTTP53CFDLMNA | |
| SCHEMBL1041877 | 0.88 | METTL3 (0.63) | METTL3MAPTCFDP2RX7GAA | |
| SCHEMBL1045107 | 0.88 | METTL3 (0.63) | METTL3MAPTCFDP2RX7GAA | |
| SCHEMBL1041876 | 0.88 | METTL3 (0.63) | METTL3MAPTCFDP2RX7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |