Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946722 | 1.00 | MAPT (0.48) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL2946721 | 1.00 | MAPT (0.48) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL295663 | 1.00 | MAPT (0.48) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL3240389 | 1.00 | MAPT (0.48) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL11960058 | 1.00 | MAPT (0.48) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL295662 | 1.00 | MAPT (0.48) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| Ammonia Solution, Strong SCHEMBL27542434 | 0.96 | MAPT (0.46) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| Bicarbonate SCHEMBL7194541 | 0.94 | CYP1A2 (0.53) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL11807539 | 0.87 | CA1 (0.50) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 | |
| SCHEMBL11807547 | 0.87 | CA1 (0.50) | MAPTALDH1A1CYP3A4KDM4ECTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243543-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2014-08-28 | — | — | US | disclosed |
| US-8716507-B2 | Iron(II) catalysts containing diimino-diphosphine tetradentate ligands and their synthesis | THE GOVERNING COUNCIL OF UNIVERSITY OF TORONTO (CA) | 2014-05-06 | — | — | US | disclosed |
| US-20100145087-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145087-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | FTH1, FECH, IDH1 | MAPT 3734/4885ALDH1A1 566/4885CYP3A4 2366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.