Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616343 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL616342 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9887225 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL7733836 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3833315 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL12263192 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9887265 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3792447 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3836511 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL12262011 | 1.00 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745462-B2 | Quinoline-2-one derivatives for the treatment of airways diseases | NOVARTIS AG (CH) | 2010-06-29 | — | — | US | disclosed |