SCHEMBL324042

SCHEMBL324042

C=CC[Si](N)(N)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23711598 0.77
SCHEMBL253425 0.77 ALDH1A1 (0.38)
SCHEMBL6433215 0.72
SCHEMBL235304 0.67 TSHR (0.33)
SCHEMBL1726461 0.67 TSHR (0.33)
SCHEMBL18687128 0.67 ALDH1A1 (0.35)
SCHEMBL1046273 0.65
SCHEMBL692155 0.64 TSHR (0.31)
SCHEMBL17201496 0.64 TSHR (0.31)
SCHEMBL5668681 0.62 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408786-B1 NOVEL SILANE COMPOUNDS HAVING A CYCLIC CARBON CHAIN INCLUDING AN ALKYNE FUNCTION FOR FUNCTIONALISING SOLID SUBSTRATES AND IMMOBILISING BIOLOGICAL MOLECULES ON SAID SUBSTRATES COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-07-23 EP claimed
US-8093313-B2 Tissue scaffolding composites EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2012-01-10 US claimed
US-20110097801-A1 TISSUE SCAFFOLDING COMPOSITES CRESTLINE DIRECT FINANCE, L.P. 2011-04-28 US claimed
US-20080090010-A1 Hydrophobic Coating Composition NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2008-04-17 US claimed
WO-2005068400-A1 HYDROPHOBIC COATING COMPOSITION NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2005-07-28 WO claimed
US-8093313-B2 Tissue scaffolding composites EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2012-01-10 US disclosed
US-20110097801-A1 TISSUE SCAFFOLDING COMPOSITES CRESTLINE DIRECT FINANCE, L.P. 2011-04-28 US disclosed
US-20080090010-A1 Hydrophobic Coating Composition NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2008-04-17 US disclosed
EP-1650254-A1 Seal with reduced torque, process for obtaining, its use as seal in flap valve and flap valve Carl Freudenberg KG (DE) 2006-04-26 EP disclosed
WO-2005068400-A1 HYDROPHOBIC COATING COMPOSITION NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2005-07-28 WO disclosed
EP-1471180-A2 Siliconized interlining, production process and use thereof Carl Freudenberg KG (DE) 2004-10-27 EP disclosed