Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | GAA | P10253 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | SNCA | P37840 | 3/20 | 0.68 |
| ▸ | BCHE | P06276 | 2/20 | 0.68 |
| ▸ | ACHE | P22303 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenothiazine SCHEMBL561001 | 0.90 | NOX1 (0.77) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL27875754 | 0.88 | NOX1 (0.74) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL2504207 | 0.82 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29352248 | 0.82 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29349533 | 0.82 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL9114 | 0.82 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL6315328 | 0.82 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL23683396 | 0.80 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL22467844 | 0.80 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL1470990 | 0.80 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116611-A1 | FORMULATION FOR METHYLENE BLUE AND METHOD | Universite de Bordeaux (FR) | 2021-06-17 | — | — | WO | claimed |
| WO-2024044760-A1 | DENDRIMER CONJUGATES OF ANTIDEPRESSANT AND ANTIPSYCHOTIC AGENTS AND THEIR METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2021116611-A1 | FORMULATION FOR METHYLENE BLUE AND METHOD | Universite de Bordeaux (FR) | 2021-06-17 | — | — | WO | disclosed |
| US-20180280620-A1 | SHIVERING ADJUSTMENT INFUSION SYSTEM AND METHOD | SEIRATHERM GmbH (DE) | 2018-10-04 | — | — | US | disclosed |
| EP-3355960-A1 | SHIVERING ADJUSTMENT INFUSION SYSTEM AND METHOD | Seiratherm GmbH (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-2118048-B1 | MALE CONTRACEPTIVE | AMOBI NNAEMEKA IKECHUKWU (GB) | 2016-11-23 | — | — | EP | disclosed |
| US-8927579-B2 | Male contraceptive | Amobi, Nnaemkea Ikechukwu (GB) | 2015-01-06 | — | — | US | disclosed |
| US-8778968-B2 | — | — | 2014-07-15 | — | — | US | disclosed |
| US-20100178333-A1 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | ASTRON RESEARCH LIMITED (IN) | 2010-07-15 | — | — | US | disclosed |
| US-20100029624-A1 | Male Contraceptive | KING'S COLLEGE LONDON (GB) | 2010-02-04 | — | — | US | disclosed |
| EP-1976487-A2 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | Astron Research Limited (IN) | 2008-10-08 | — | — | EP | disclosed |
| WO-2008087421-A2 | MALE CONTRACEPTIVE | KING'S COLLEGE LONDON (GB) | 2008-07-24 | — | — | WO | disclosed |
| WO-2007086079-A2 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | ASTRON RESEARCH LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |
| EP-1212000-B1 | SYSTEM FOR CONTROLLING BODY TEMPERATURE WHILE REDUCING SHIVERING | RADIANT MEDICAL INC (US) | 2006-01-04 | — | — | EP | disclosed |
| US-6572638-B1 | Method of controlling body temperature while inhibiting thermoregulatory responses | RADIANT MEDICAL, INC. | 2003-06-03 | — | — | US | disclosed |
| EP-1212000-A4 | METHOD OF CONTROLLING BODY TEMPERATURE WHILE REDUCING SHIVERING | RADIANT MEDICAL INC (US) | 2002-10-25 | — | — | EP | disclosed |
| EP-1212000-A1 | SYSTEM FOR CONTROLLING BODY TEMPERATURE WHILE REDUCING SHIVERING | Radiant Medical, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6231594-B1 | Method of controlling body temperature while reducing shivering | RADIANT MEDICAL, INC. | 2001-05-15 | — | — | US | disclosed |
| WO-2001010323-A1 | METHOD OF CONTROLLING BODY TEMPERATURE WHILE REDUCING SHIVERING | RADIANT MEDICAL, INC. (US) | 2001-02-15 | — | — | WO | disclosed |
| US-4758562-A | Method for inducing hypothermia and/or poikilothermia | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1988-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029624-A1 | Male Contraceptive | NR5A1, AR, CYP19A1 | NOX1 1115/4885MAPT 4450/4885GAA 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.