Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.52 |
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68421 | 0.80 | PPARG (0.56) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL3900454 | 0.77 | FFAR1 (0.62) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL3265588 | 0.77 | FFAR1 (0.53) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL1848812 | 0.77 | PPARG (0.60) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL2883389 | 0.76 | PPARG (0.56) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL3116782 | 0.74 | PPARG (0.65) | FFAR1PPARGHRH3PPARARXRA | |
| SCHEMBL3117517 | 0.74 | PPARG (0.62) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL9570670 | 0.74 | FFAR1 (0.71) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL5883336 | 0.74 | PPARG (0.52) | FFAR1PPARGHRH3PPARACYP3A4 | |
| SCHEMBL1072226 | 0.73 | FFAR1 (0.77) | FFAR1PPARGHRH3PPARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010013141-A2 | SUBSTANTIALLY PURE ROSIGLITAZONE HYDROGEN SULFATE | ACTAVIS GROUP PTC EHF (IS) | 2010-02-04 | — | — | WO | claimed |