SCHEMBL3242169

SCHEMBL3242169

CCC(OC(=O)N1CCC(Oc2cc(N3CCc4cc(S(C)(=O)=O)ccc43)ncn2)CC1)C(C)I

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3240822 0.91 GPR119 (0.85) GPR119
SCHEMBL3236294 0.90 GPR119 (0.84) GPR119
SCHEMBL288614 0.89 GPR119 (1.00) GPR119
SCHEMBL3238949 0.88 GPR119 (0.91) GPR119
SCHEMBL3239744 0.87 GPR119 (0.84) GPR119
SCHEMBL3236279 0.87 GPR119 (0.80) GPR119
SCHEMBL3235135 0.86 GPR119 (0.82) GPR119
SCHEMBL3245186 0.86 GPR119 (0.88) GPR119
SCHEMBL3237911 0.86 GPR119 (0.81) GPR119
SCHEMBL3245299 0.85 GPR119 (0.83) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210886-A1 PYRIMIDYL INDOLINE COMPOUND Daiichi Sankyo Company, Limited (JP) 2010-07-28 EP disclosed