Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245401 | 0.91 | F10 (0.41) | F10ALDH1A1KDM4ETP53SMN1; SMN2 | |
| SCHEMBL3507659 | 0.91 | F10 (0.43) | F10DGAT2ALDH1A1KDM4ELMNA | |
| SCHEMBL12311487 | 0.83 | F10 (0.46) | F10ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL3246178 | 0.83 | F10 (0.43) | F10SSTR5 | |
| SCHEMBL3508057 | 0.83 | F10 (0.45) | F10DGAT2ALDH1A1KDM4ELMNA | |
| SCHEMBL3506367 | 0.81 | F10 (0.43) | F10 | |
| SCHEMBL3507693 | 0.78 | L3MBTL1 (0.40) | ALDH1A1KDM4ETP53SMN1; SMN2OPRM1 | |
| SCHEMBL3507730 | 0.74 | F10 (0.45) | F10SSTR5 | |
| SCHEMBL3508891 | 0.73 | F10 (0.45) | F10 | |
| SCHEMBL8225103 | 0.73 | F10 (0.47) | F10DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029546-B1 | ARYL-SUBSTITUTED HETEROCYCLES, AND USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-07-28 | — | — | EP | disclosed |