Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242742 | 0.78 | ADORA3 (0.34) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6422442 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL31311242 | 0.68 | F2 (0.43) | F2PRSS1DAOPRSS2PRSS3 | |
| SCHEMBL7409413 | 0.67 | CNR1 (0.39) | F2PRSS1DAOPRSS2PRSS3 | |
| SCHEMBL7409009 | 0.64 | F2 (0.43) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18235949 | 0.59 | HTT (0.52) | F2HPGD | |
| SCHEMBL4904924 | 0.58 | F2 (0.67) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL9886714 | 0.57 | KCNN4 (0.44) | DAOTSHR | |
| SCHEMBL23995203 | 0.55 | KCNN4 (0.47) | TSHR | |
| SCHEMBL15281776 | 0.54 | CNR1 (0.46) | DAOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589029-B1 | Pyrazinone protease inhibitors | ORTHO MCNEIL PHARM INC (US) | 2010-03-17 | — | — | EP | claimed |