Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632865 | 0.75 | BPTF (0.39) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30488536 | 0.74 | CA12 (0.37) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18502841 | 0.74 | CA12 (0.37) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13058477 | 0.69 | CHRNA7 (0.40) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2320891 | 0.69 | BPTF (0.36) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2131511 | 0.69 | BPTF (0.56) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12890925 | 0.69 | NOS3 (0.30) | — | |
| SCHEMBL12356661 | 0.69 | NOS3 (0.34) | — | |
| SCHEMBL25258684 | 0.67 | TLR8 (0.43) | LMNASMN1; SMN2BPTF | |
| SCHEMBL30488561 | 0.67 | TLR8 (0.43) | LMNASMN1; SMN2BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |