SCHEMBL32424912

SCHEMBL32424912

CON(C)C(=O)c1cccc(C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
PARP1 P09874 1/20 0.52
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.46
TP53 P04637 1/20 0.46
CTNNB1 P35222 1/20 0.45
WNT3A P56704 1/20 0.45
KCNK3 O14649 2/20 0.45
KCNK9 Q9NPC2 2/20 0.45
KCNH2 Q12809 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MLYCD O95822 1/20 0.44
POLB P06746 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ABCB1 P08183 1/20 0.43
HSD17B1 P14061 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2652369 1.00 HPGD (0.57) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL15281239 0.89 KMT2A (0.50) HPGDTDP1PARP1MEN1KMT2A
SCHEMBL16214051 0.84 MEN1 (0.46) HPGDTDP1SMN1; SMN2MEN1KMT2A
SCHEMBL1515904 0.82 CA12 (0.50) PARP1MLYCDPOLBNPC1RAB9A
SCHEMBL23782 0.81 HPGD (0.65) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL29637011 0.81 HPGD (0.65) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL6493529 0.81 MLYCD (0.45) HPGDTDP1SMN1; SMN2MEN1KMT2A
SCHEMBL4719735 0.81 TPMT (0.46) HPGDMLYCDABCB1
SCHEMBL8271457 0.81 PARP1 (0.54) TDP1PARP1MEN1KMT2AMLYCD
SCHEMBL111914 0.81 HPGD (0.51) HPGDPARP1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010881-A Synthesis method of 3-phenoxy-2-arylbenzofuran compound 南京工业大学 2026-05-12 CN disclosed