SCHEMBL3242641

SCHEMBL3242641

CN1[C@@H]2C[CH]C[C@H]1CC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2386084 1.00
SCHEMBL157432 1.00
SCHEMBL1289780 0.88 MAPK1 (0.46)
SCHEMBL16338628 0.88 MAPK1 (0.46)
SCHEMBL1005825 0.77 HSD11B1 (0.31)
SCHEMBL278331 0.75
SCHEMBL13676319 0.75
SCHEMBL3414619 0.75
SCHEMBL3411877 0.75
SCHEMBL1922532 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3720852-A1 FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2020-10-14 EP claimed
US-20200308168-A1 FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2020-10-01 US claimed
WO-2019110521-A1 FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2019-06-13 WO claimed
US-8183380-B2 2-aminoquinolines HOFFMANN-LA ROCHE INC. (US) 2012-05-22 US claimed
US-20090227570-A1 2-AMINOQUINOLINES HOFFMANN-LA ROCHE, INC. 2009-09-10 US claimed
EP-1025099-A1 BIS-QUATERNARY AMMONIUM DERIVATIVES AS NEUROMUSCULAR RELAXANTS Gyermek, Laszlo (US) 2000-08-09 EP claimed
WO-1999021854-A1 BIS-QUATERNARY AMMONIUM DERIVATIVES AS NEUROMUSCULAR RELAXANTS NEWLAXANT LLC (US) 1999-05-06 WO claimed
EP-0361629-B1 Heterocyclic compounds WYETH JOHN & BROTHER LTD (GB) 1994-06-15 EP claimed
US-5106843-A Treatment of migraine, emesis, anxiety, gastrointestinal disorders, psychological disorders AMERICAN HOME PRODUCTS CORPORATION (US) 1992-04-21 US claimed
EP-0323077-B1 HETEROCYCLIC COMPOUNDS JOHN WYETH &amp; BROTHER LIMITED (GB) 1991-09-11 EP claimed
WO-1991004252-A1 NEW ESTERS OF THIENYL CARBOXYLIC ACIDS AND AMINO ALCOHOLS, THEIR QUATERNIZATION PRODUCTS, AND MANUFACTURE AND USE OF SAID COMPOUNDS BOEHRINGER INGELHEIM KG (DE) 1991-04-04 WO claimed
US-4983600-A Antiemetics, antianxiety agents, gastrointestinal disorders JOHN WYETH & BROTHER LIMITED (GB) 1991-01-08 US claimed
EP-0361629-A2 Heterocyclic compounds JOHN WYETH &amp; BROTHER LIMITED (GB) 1990-04-04 EP claimed
EP-0323077-A1 Heterocyclic compounds JOHN WYETH &amp; BROTHER LIMITED (GB) 1989-07-05 EP claimed
US-20240067646-A1 COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY HOFFMANN-LA ROCHE INC. 2024-02-29 US disclosed
EP-3634953-B1 COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE PTC THERAPEUTICS INC (US) 2024-01-03 EP disclosed
US-20230310651-A1 METHODS FOR MODULATING RNA SPLICING PTC THERAPEUTICS, INC. (US) 2023-10-05 US disclosed
EP-0306148-A2 Azabicyclic ethers JOHN WYETH &amp; BROTHER LIMITED (GB) 1989-03-08 EP disclosed
US-4704387-A N-benzyl, phenethyl, methoxyethyl or allyl substituted benzylphthalazinones having antiallergic and antihistamine action ASTA-WERKE AKTIENGESELLSCHAFT, CHEMISCHE FABRIK (DE) 1987-11-03 US disclosed
US-4410527-A ANTIULCER AGENTS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-10-18 US disclosed