Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.62 |
| ▸ | BID | P55957 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435204 | 1.00 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL28373053 | 0.98 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL6901338 | 0.94 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL9484841 | 0.88 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL28315886 | 0.84 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL8133467 | 0.84 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL7916115 | 0.84 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL4615949 | 0.84 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| Hydrogen Peroxide SCHEMBL11209358 | 0.83 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL9640378 | 0.83 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039531-A1 | THERAPEUTIC COMPOUNDS | RESOLVYX PHARMACEUTICALS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |