SCHEMBL7916115

SCHEMBL7916115

CCCCCCc1ccccc1C(O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 10/20 0.62
CYSLTR1 Q9Y271 10/20 0.62
BID P55957 3/20 0.50
MCL1 Q07820 3/20 0.50
BCL2L1 Q07817 2/20 0.50
BAK1 Q16611 2/20 0.50
KAT8 Q9H7Z6 2/20 0.50
LIPG Q9Y5X9 1/20 0.50
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
EP300 Q09472 1/20 0.50
KAT2A Q92830 1/20 0.50
KAT2B Q92831 1/20 0.50
KAT5 Q92993 1/20 0.50
SAE1 Q9UBE0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890650 0.98 CYSLTR2 (0.59) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL4029728 0.87 CYSLTR2 (0.46) CYSLTR2CYSLTR1PPARGPPARA
SCHEMBL9068158 0.87 BID (0.54) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL11011747 0.86 CYSLTR2 (0.46) CYSLTR2CYSLTR1
SCHEMBL11011751 0.85 BID (0.51) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL9667336 0.85 CYSLTR2 (0.56) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL28315886 0.84 CYSLTR2 (0.62) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL10435204 0.84 CYSLTR2 (0.62) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL3242848 0.84 CYSLTR2 (0.62) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL9504738 0.84 CYSLTR2 (0.54) CYSLTR2CYSLTR1BIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104174184-B A kind of method of multi-walled carbon nano-tubes thin layer chromatography resolving chiral medicine 红河学院 2016-10-26 CN claimed
CN-103772188-B The preparation method of R-(+)-α-Cyclo hexyl mandelic acid CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO., LTD. (CN) 2015-09-23 CN claimed
CN-103103156-B Brevibacterium and hydrolytic synthesis method of alpha-cyclo hexyl mandelic acid through nitrile and derivative UNIV CHANGZHOU 2015-04-22 CN claimed
CN-104174184-A Method for separating chiral drug by using multi-wall carbon nano-tube thin-layer chromatography HONGHE COLLEGE 2014-12-03 CN claimed
CN-102796874-B Technology for recovering gold and silver from electronic waste by new biological method FANG XIAOLING 2014-12-03 CN claimed
CN-103772188-A Preparation method of R-(+)-alpha-cyclohexyl mandelic acid CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD 2014-05-07 CN claimed
CN-103103156-A Brevibacterium and hydrolytic synthesis method of alpha-cyclo hexyl mandelic acid through nitrile and derivative UNIV CHANGZHOU 2013-05-15 CN claimed
CN-102796874-A Technology for recovering gold and silver from electronic waste by new biological method XIAOLING FANG 2012-11-28 CN claimed
CN-104174184-B A kind of method of multi-walled carbon nano-tubes thin layer chromatography resolving chiral medicine 红河学院 2016-10-26 CN disclosed
CN-105296512-A Nitrilases, nucleic acids encoding them and methods for making and using them BASF ENZYMES LLC 2016-02-03 CN disclosed
CN-103772188-B The preparation method of R-(+)-α-Cyclo hexyl mandelic acid CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO., LTD. (CN) 2015-09-23 CN disclosed
CN-103772188-B The preparation method of R-(+)-α-Cyclo hexyl mandelic acid CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO., LTD. (CN) 2015-09-23 CN disclosed
CN-103772188-B The preparation method of R-(+)-α-Cyclo hexyl mandelic acid CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO., LTD. (CN) 2015-09-23 CN disclosed
CN-102796750-B The nucleic acid of nitrilase, encoding nitrilase enzyme, and the method preparing and use them BASF ENZYMES LLC (US) 2015-09-16 CN disclosed
CN-102202664-A Pharmaceutical product comprising a muscarinic receptor antagonist and a beta-2-adrenoceptor agonist ASTRAZENECA AB 2011-09-28 CN disclosed
CN-102202665-A Pharmaceutical product comprising a muscarinic receptor antagonist and a second active ingredient ASTRAZENECA AB 2011-09-28 CN disclosed
CN-102001904-A Novel chiral separation method HUNAN INST SCIENCE & TECH 2011-04-06 CN disclosed
CN-101624339-A Technology for extracting and separating hydrophobicity enantiomer with water soluble Beta-cyclodextrin HUNAN INST SCIENCE & TECH 2010-01-13 CN disclosed
CN-1849391-A Nitrilases, nucleic acids encoding nitrilases, and methods of making and using the same DIVERSA CORP (US) 2006-10-18 CN disclosed
US-6207852-B1 THERAPY FOR INCONTINENCE; CROHN'S DISEASE; MUSCLE RELAXANTS BRIDGE PHARMA, INC. 2001-03-27 US disclosed