Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246159 | 0.92 | PARP1 (0.47) | PARP1ALDH1A1MAPTGAARAB9A | |
| SCHEMBL3251023 | 0.88 | CDC25A (0.43) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3249681 | 0.85 | PARP1 (0.44) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3251324 | 0.85 | BAZ2A (0.42) | PARP1 | |
| SCHEMBL3251225 | 0.85 | CSNK2A1 (0.42) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3253850 | 0.85 | SCN9A (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL3243023 | 0.85 | PIM1 (0.41) | — | |
| SCHEMBL3252051 | 0.84 | PARP1 (0.41) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3249392 | 0.84 | PARP1 (0.46) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3253872 | 0.84 | PARP1 (0.41) | PARP1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |