Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235400 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PDCD4DAGLATDP1 | |
| SCHEMBL3238484 | 0.94 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PDCD4DAGLATDP1 | |
| SCHEMBL11879201 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PDCD4DAGLATDP1GPR84 | |
| SCHEMBL27891494 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PDCD4DAGLATDP1GPR84 | |
| SCHEMBL21081918 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PDCD4DAGLATDP1GPR84 | |
| SCHEMBL28001429 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PDCD4DAGLATDP1GPR84 | |
| SCHEMBL17253429 | 0.89 | ALDH1A1 (0.47) | ALDH1A1PDCD4DAGLATDP1GPR84 | |
| Oxirane SCHEMBL8570225 | 0.87 | DAGLA (0.47) | ALDH1A1PDCD4DAGLATDP1GPR84 | |
| SCHEMBL13589341 | 0.87 | — | — | |
| SCHEMBL990913 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072696-A1 | SUBSTITUTED 3-HYDROXY-DELTA-LACTONES FROM EPOXIDES | NATIONAL SCIENCE FOUNDATION | 2018-03-15 | — | — | US | disclosed |
| US-9719030-B2 | Epoxide-based hydrogen sulfide scavengers | ECOLAB USA INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-9719030-B2 | Epoxide-based hydrogen sulfide scavengers | ECOLAB USA INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-9676743-B2 | Substituted 3-hydroxy-δ-lactones from epoxides | CORNELL UNIVERSITY (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150001132-A1 | EPOXIDE-BASED HYDROGEN SULFIDE SCAVENGERS | ECOLAB USA INC. | 2015-01-01 | — | — | US | disclosed |
| US-20150001132-A1 | EPOXIDE-BASED HYDROGEN SULFIDE SCAVENGERS | ECOLAB USA INC. | 2015-01-01 | — | — | US | disclosed |
| WO-2014210166-A1 | EPOXIDE-BASED HYDROGEN SULFIDE SCAVENGERS | ECOLAB USA INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-20140107339-A1 | SUBSTITUTED 3-HYDROXY-DELTA-LACTONES FROM EPOXIDES | CORNELL UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-8530677-B2 | Substituted 3-hydroxy-delta-lactones from epoxides | CORNELL UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-20100145046-A1 | Substituted 3-hydroxy-delta-lactones from epoxides | ENERGY, UNITED STATES DEPARTMENT OF | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145046-A1 | Substituted 3-hydroxy-delta-lactones from epoxides | EBP, CYP8B1, HSD3B2 | ALDH1A1 319/4885SMN1; SMN2 4636/4885PDCD4 2877/4885 |
| US-20180072696-A1 | SUBSTITUTED 3-HYDROXY-DELTA-LACTONES FROM EPOXIDES | EBP, CYP8B1, HSD3B2 | ALDH1A1 319/4885SMN1; SMN2 4636/4885PDCD4 2877/4885 |
| US-20140107339-A1 | SUBSTITUTED 3-HYDROXY-DELTA-LACTONES FROM EPOXIDES | EBP, CYP8B1, HSD3B2 | ALDH1A1 319/4885SMN1; SMN2 4636/4885PDCD4 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.