Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373633 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL28521007 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL27839292 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL29843712 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL7255990 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL28907776 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL30176799 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH | |
| Hydrochloric Acid SCHEMBL28750117 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH | |
| Hydrochloric Acid SCHEMBL27747957 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH | |
| Hydrochloric Acid SCHEMBL27857053 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-111892599-B | Synthesis method of 2,5-diazabicyclo [2.2.2] octane-2-tert-butyl carboxylate | 黄芳（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115315424-A | 2-methyl-aza-quinazolines | 拜耳公司 | 2022-11-08 | — | — | CN | claimed |
| CN-109661396-B | Spiro-fused cyclic ureas as ROCK inhibitors | 百时美施贵宝公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114667145-A | Molecules that bind to TDP-43 for the treatment of amyotrophic lateral sclerosis and related disorders | 拜尔哈文制药股份有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-113135921-B | Dihydropyrimidine-spiro derivative and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | claimed |
| CN-113135921-A | Dihydropyrimidine-spiro derivative and preparation method and application thereof | 山东大学 | 2021-07-20 | — | — | CN | claimed |
| CN-109415371-B | 2-amido thiazole derivative and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-112574085-A | Preparation method of 5-amino-2-azaspiro [3.4] octane-2-carboxylic acid tert-butyl ester | 南通药明康德医药科技有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-111892599-A | Synthesis method of 2, 5-diazabicyclo [2.2.2] octane-2-carboxylic acid tert-butyl ester | 黄芳 | 2020-11-06 | — | — | CN | claimed |
| CN-109415371-A | Novel 2-acylamino thiazole derivative and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-106517049-B | 360 ° of large parts turnover devices of one kind and its working method | 江苏建筑职业技术学院 | 2018-07-20 | — | — | CN | claimed |
| CN-107873023-A | 3-alkyl-4-amido-bicyclo [4, 5, 0] hydroxamic acids as HDAC inhibitors | 福马治疗股份有限公司 | 2018-04-03 | — | — | CN | claimed |
| CN-118344370-A | Isoindolinone and indazole compounds for EGFR degradation | C4医药公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-0411460-B1 | Perfumery composition comprising 2-cyclohexylpropionic acid or its derivative | KAO CORP (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5049544-A | Perfumery composition comprising 2-cyclohexylpropionic acid or its derivative | KAO CORPORATION (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0411460-A1 | Perfumery composition comprising 2-cyclohexylpropionic acid or its derivative | KAO CORPORATION (JP) | 1991-02-06 | — | — | EP | disclosed |
| CN-86105905-A | Process for the preparation of cephalosporin nucleus derivatives and their use in medicaments | — | 1987-07-29 | — | — | CN | disclosed |