Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373633 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL28521007 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL27839292 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL29843712 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL28907776 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL3243083 | 1.00 | CA1 (0.50) | CA1ACE2ZDHHC7CA2FAAH | |
| SCHEMBL30176799 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH | |
| Hydrochloric Acid SCHEMBL28750117 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH | |
| Hydrochloric Acid SCHEMBL27747957 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH | |
| Hydrochloric Acid SCHEMBL27857053 | 0.98 | CA1 (0.48) | CA1ACE2ZDHHC7CA2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396477-A | Pyridyl-substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-01-12 | — | — | CN | claimed |
| CN-113135921-A | Dihydropyrimidine-spiro derivative and preparation method and application thereof | 山东大学 | 2021-07-20 | — | — | CN | claimed |
| CN-107873023-A | 3-alkyl-4-amido-bicyclo [4, 5, 0] hydroxamic acids as HDAC inhibitors | 福马治疗股份有限公司 | 2018-04-03 | — | — | CN | claimed |
| WO-2003053941-A2 | BARBITURIC ACID DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND/OR MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | claimed |
| CN-113950477-B | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | disclosed |
| CN-117940133-A | Therapeutic agents for degradation of mutant BRAF | C4医药公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-116964046-B | PLK4 inhibitors and uses thereof | 上海齐鲁制药研究中心有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117820292-A | Quinazolinone derivatives, preparation method and application thereof | 合肥医工医药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117715658-A | Method for inhibiting RAS | 锐新医药公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-102712641-A | MK2 inhibitors | MSD OSS BV | 2012-10-03 | — | — | CN | disclosed |
| CN-101679456-B | Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol 3-kinase | HOFFMANN LA ROCHE | 2012-09-05 | — | — | CN | disclosed |
| CN-102382129-A | Spirocycles-substituted phosphodiesterase inhibitor | KBP BIOSCIENCES CO LTD | 2012-03-21 | — | — | CN | disclosed |
| CN-102365276-A | Substituted spiro-amide compounds | GRUENENTHAL GMBH | 2012-02-29 | — | — | CN | disclosed |
| CN-101679456-A | Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol 3-kinase | HOFFMANN LA ROCHE | 2010-03-24 | — | — | CN | disclosed |
| CN-101528225-A | 2-aminobenzoxazole carboxamides as 5HT3 modulators | AMR TECHNOLOGY INC (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101305005-A | Novel diazaspiroalkanes and their use for treatment of CCR8 mediated diseases | ASTRAZENECA AB (SE) | 2008-11-12 | — | — | CN | disclosed |
| WO-2003053941-A2 | BARBITURIC ACID DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND/OR MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |