Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239881 | 0.93 | SLC22A12 (0.37) | SLC22A12MCL1LMNACNR2ALDH1A1 | |
| SCHEMBL3247016 | 0.93 | SLC22A12 (0.38) | SLC22A12LMNACNR2ALDH1A1 | |
| SCHEMBL3241585 | 0.91 | SLC22A12 (0.39) | SLC22A12PLA2G4ALMNACNR2ALDH1A1 | |
| SCHEMBL3239637 | 0.91 | SLC22A12 (0.39) | SLC22A12LMNACNR2ALDH1A1 | |
| SCHEMBL3247125 | 0.91 | CNR2 (0.41) | SLC22A12LMNACNR2ALDH1A1 | |
| SCHEMBL3246470 | 0.90 | SLC22A12 (0.41) | SLC22A12MCL1LMNAALDH1A1 | |
| SCHEMBL3240020 | 0.90 | CNR2 (0.38) | SLC22A12MCL1LMNACNR2ALDH1A1 | |
| SCHEMBL3241672 | 0.90 | PLA2G4A (0.38) | SLC22A12PLA2G4ALMNACNR2ALDH1A1 | |
| SCHEMBL3245321 | 0.89 | CNR2 (0.45) | SLC22A12LMNACNR2 | |
| SCHEMBL3247047 | 0.89 | CNR1 (0.39) | SLC22A12LMNACNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |