⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820883 | 0.80 | — | — | |
| SCHEMBL1831644 | 0.80 | KCNH2 (0.42) | — | |
| SCHEMBL23192898 | 0.80 | — | — | |
| SCHEMBL24211391 | 0.75 | — | — | |
| SCHEMBL24050941 | 0.75 | CYP3A4 (0.40) | — | |
| SCHEMBL28089810 | 0.74 | EPHB4 (0.49) | — | |
| SCHEMBL179541 | 0.74 | — | — | |
| SCHEMBL8369465 | 0.73 | NPBWR1 (0.60) | — | |
| SCHEMBL17723733 | 0.73 | CYP19A1 (0.44) | — | |
| SCHEMBL18148936 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068347-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-04-03 | — | — | WO | claimed |
| CN-114634627-B | One-dimensional pyrazole mixed-valence copper fullerene coordination polymer and preparation method and application thereof | 汕头大学 | 2023-02-28 | — | — | CN | claimed |
| CN-114634627-A | One-dimensional pyrazole mixed-valence copper fullerene coordination polymer and preparation method and application thereof | 汕头大学 | 2022-06-17 | — | — | CN | claimed |
| CN-113816850-A | Synthesis method of trifluoropropyl acetate | 南通宝凯药业有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-111875543-A | Preparation method of 4-trifluoromethylpyrazole | 金凯(辽宁)化工有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | claimed |
| CN-122036605-A | Antagonists of GPR39 proteins | 俄勒冈健康科学大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20260132109-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2026-05-14 | — | — | US | disclosed |
| EP-3856179-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| US-20260124204-A1 | METALLOENZYME INHIBITOR COMPOUNDS | EIKONIZO THERAPEUTICS, INC. (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4568960-B1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2026-04-29 | — | — | EP | disclosed |
| EP-4733303-A1 | MUSCARINIC M4 RECEPTOR AGONIST AND USE THEREOF | Haisco Pharmaceutical Group Co., Ltd. (CN) | 2026-04-29 | — | — | EP | disclosed |
| US-20260108546-A1 | GIP RECEPTOR AGONIST COMPOUNDS | LILLY CO ELI (US) | 2026-04-23 | — | — | US | disclosed |
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2005-09-22 | — | — | US | disclosed |
| EP-1527067-A1 | 4-TRIFLUOROMETHYLPYRAZOLYL SUBSTITUTED PYRIDINES AND PYRIMIDINES | Bayer CropScience GmbH (DE) | 2005-05-04 | — | — | EP | disclosed |
| EP-1527069-A2 | PYRIDINES AND PYRIMIDINES SUBSTITUTED BY 4-TRIFLUOROMETHYLPYRAZOLYL | Bayer CropScience GmbH (DE) | 2005-05-04 | — | — | EP | disclosed |
| US-20040082475-A1 | 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-04-29 | — | — | US | disclosed |
| US-20040072692-A1 | 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-04-15 | — | — | US | disclosed |
| WO-2004013129-A1 | 4-TRIFLUOROMETHYLPYRAZOLYL SUBSTITUTED PYRIDINES AND PYRIMIDINES | BAYER CROPSCIENCE GMBH (DE) | 2004-02-12 | — | — | WO | disclosed |
| WO-2004013131-A2 | PYRIDINES AND PYRIMIDINES SUBSTITUTED BY 4-TRIFLUOROMETHYLPYRAZOLYL | BAYER CROPSCIENCE GMBH (DE) | 2004-02-12 | — | — | WO | disclosed |