Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92709 | 0.93 | GAA (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL11699403 | 0.91 | GAA (0.52) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL28158933 | 0.91 | GAA (0.52) | CYP1A2GAAMGAMSIMGAM2 | |
| Water SCHEMBL9797230 | 0.91 | GAA (0.52) | CYP1A2GAAMGAMSIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL27646294 | 0.91 | GAA (0.57) | CYP1A2GAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL1326418 | 0.88 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL11060538 | 0.88 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL4559194 | 0.88 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL9525462 | 0.88 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL7695273 | 0.88 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450476-B2 | Making drospirenone; chemical intermediates e.g. carbethoxy-drospirenone; industrial scale, safe (no chromium catalyst), meets purity requirements | RICHTER GEDEON NYRT. (HU) | 2013-05-28 | — | — | US | claimed |
| US-8309712-B2 | Synthesis of drospirenone in only eight steps; claimed intermediates; readily available raw materials; simple crystallization purification; no hazardous materials; yield | RICHTER GEDEON NYRT. (HU) | 2012-11-13 | — | — | US | claimed |
| CN-101061132-B | Process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-17 alpha-pregn-4-en-3-one-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYESZET | 2011-03-30 | — | — | CN | claimed |
| CN-101061133-B | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-hydroxyacid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZET | 2011-01-26 | — | — | CN | claimed |
| EP-1831239-B1 | A PROCESS FOR THE PREPARATION OF 17-HYDROXY-6 BETA, 7 BETA, 15 BETA, 16 BETA -BISMETHYLENE-17 ALPHA-PREGN-4-ENE-3-ONE-21-CARBOXYLIC ACID LAMBDA-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS | RICHTER GEDEON NYRT (HU) | 2010-03-24 | — | — | EP | claimed |
| US-20080200668-A1 | Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-08-21 | — | — | US | claimed |
| US-20080194812-A1 | Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-08-14 | — | — | US | claimed |
| CN-101061133-A | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZETI GYAR R (HU) | 2007-10-24 | — | — | CN | claimed |
| CN-101061132-A | Process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-17 alpha-pregn-4-en-3-one-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZETI GYAR R (HU) | 2007-10-24 | — | — | CN | claimed |
| EP-1817326-A1 | INDUSTRIAL PROCESS FOR THE PREPERATION OF 17-HYDROXY -6 BETA, 7-BETA, 15-BETA, 16-BETA-BISMETHYLENE-3-OXO 17-ALPHA PREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE AND KEY INTERMEDIATES FOR THIS PROCESS | Richter Gedeon Vegy Szeti Gy R Rt. (HU) | 2007-08-15 | — | — | EP | claimed |
| WO-2006059167-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF 17-HYDROXY-6β,7β;15β,16β-BISMETHYLENE-3-OXO-17α-PREGN-4-ENE-21-CARBOXYLIC ACID Ϝ-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-06-08 | — | — | WO | claimed |
| US-8450476-B2 | Making drospirenone; chemical intermediates e.g. carbethoxy-drospirenone; industrial scale, safe (no chromium catalyst), meets purity requirements | RICHTER GEDEON NYRT. (HU) | 2013-05-28 | — | — | US | disclosed |
| US-8309712-B2 | Synthesis of drospirenone in only eight steps; claimed intermediates; readily available raw materials; simple crystallization purification; no hazardous materials; yield | RICHTER GEDEON NYRT. (HU) | 2012-11-13 | — | — | US | disclosed |
| CN-101061132-B | Process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-17 alpha-pregn-4-en-3-one-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYESZET | 2011-03-30 | — | — | CN | disclosed |
| CN-101061133-B | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-hydroxyacid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZET | 2011-01-26 | — | — | CN | disclosed |
| EP-0790994-A1 | HETEROCYCLE SUBSTITUTED PROPENOIC ACID DERIVATIVES AS NMDA ANTAGONISTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5563157-A | EXCITATORY AMINO ACID ANTAGONISTS | HOECHST MARION ROUSSEL INC. (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1996013501-A1 | HETEROCYCLE SUBSTITUTED PROPENOIC ACID DERIVATIVES AS NMDA ANTAGONISTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-05-09 | — | — | WO | disclosed |
| US-4321275-A | ANIMAL HUSBANDRY | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-03-23 | — | — | US | disclosed |
| EP-0035412-A1 | Amidotetrazole compounds and processes for their preparation | GLAXO GROUP LIMITED (GB) | 1981-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200668-A1 | Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | HSD17B7, CYP17A1, HSD17B11 | CYP1A2 52/4885GAA 1478/4885MGAM 400/4885 |
| US-20080194812-A1 | Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | CYP17A1, HSD17B7, HSD17B11 | CYP1A2 54/4885GAA 1795/4885MGAM 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.