Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392461 | 0.84 | CHRM2 (0.34) | GPR119NR1H2BCHECHRM2CHRM1 | |
| SCHEMBL29169857 | 0.84 | PDE4B (0.36) | GPR119NR1H2BCHEHDAC1KMT2A | |
| SCHEMBL31544790 | 0.83 | GPR119 (0.33) | GPR119NR1H2BCHECHRM2CHRM1 | |
| SCHEMBL30896825 | 0.80 | CA12 (0.31) | GPR119NR1H2 | |
| SCHEMBL2260256 | 0.74 | DPP4 (0.35) | GPR119BCHECHRM2CHRM1CHRM3 | |
| SCHEMBL28107442 | 0.71 | USP2 (0.37) | GPR119NR1H2BCHECHRM2CHRM1 | |
| SCHEMBL19892750 | 0.70 | CHRM2 (0.34) | GPR119NR1H2BCHECHRM2CHRM1 | |
| SCHEMBL28428311 | 0.68 | CHRM2 (0.39) | GPR119NR1H2BCHECHRM2CHRM1 | |
| SCHEMBL7382661 | 0.68 | NR1H2 (0.38) | NR1H2 | |
| SCHEMBL30121408 | 0.67 | CHRM2 (0.34) | GPR119NR1H2BCHECHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033980-A2 | 4-AZAINDOLE BISPHOSPHONATES | ISIS INNOVATION LTD. (GB) | 2010-03-25 | — | — | WO | disclosed |