Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147704 | 0.88 | TRPV1 (0.43) | KCNH2 | |
| SCHEMBL1147907 | 0.88 | TRPV1 (0.43) | KCNH2 | |
| SCHEMBL3252103 | 0.87 | KCNH2 (0.38) | KCNH2ALDH1A1LMNA | |
| SCHEMBL2255565 | 0.87 | KCNH2 (0.42) | KCNH2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL3252106 | 0.86 | KCNH2 (0.46) | KCNH2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3250867 | 0.83 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2255567 | 0.83 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL3252737 | 0.82 | KCNH2 (0.39) | KCNH2ALDH1A1 | |
| SCHEMBL3251533 | 0.81 | KCNH2 (0.49) | KCNH2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5748231 | 0.81 | KCNH2 (0.43) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001478-B1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-02 | — | — | EP | claimed |