Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148044 | 0.89 | TRPV1 (0.45) | KCNH2ALDH1A1LMNA | |
| SCHEMBL3244059 | 0.87 | KCNH2 (0.40) | KCNH2ALDH1A1LMNA | |
| SCHEMBL3249967 | 0.86 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3253063 | 0.84 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL3251583 | 0.83 | SLC2A1 (0.39) | — | |
| SCHEMBL1147704 | 0.81 | TRPV1 (0.43) | KCNH2 | |
| SCHEMBL1147907 | 0.81 | TRPV1 (0.43) | KCNH2 | |
| SCHEMBL3249988 | 0.80 | KCNH2 (0.48) | KCNH2ALDH1A1 | |
| SCHEMBL3251532 | 0.78 | MAOA (0.46) | KCNH2MAOAMAOBALDH1A1LMNA | |
| SCHEMBL5264336 | 0.78 | KCNH2 (0.52) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001478-B1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-02 | — | — | EP | claimed |