Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243438 | 0.93 | HSD11B1 (0.74) | IDH1HSD11B1 | |
| SCHEMBL1971811 | 0.89 | IDH1 (0.80) | IDH1HSD11B1 | |
| SCHEMBL1971809 | 0.89 | IDH1 (0.80) | IDH1HSD11B1 | |
| SCHEMBL13182659 | 0.89 | IDH1 (0.80) | IDH1HSD11B1 | |
| SCHEMBL1971806 | 0.89 | IDH1 (0.80) | IDH1HSD11B1 | |
| SCHEMBL14972845 | 0.88 | IDH1 (0.82) | IDH1HSD11B1 | |
| SCHEMBL14972814 | 0.88 | HSD11B1 (0.76) | IDH1HSD11B1 | |
| SCHEMBL2007321 | 0.86 | IDH1 (1.00) | IDH1HSD11B1 | |
| SCHEMBL2011257 | 0.86 | IDH1 (1.00) | IDH1HSD11B1 | |
| SCHEMBL13182783 | 0.86 | IDH1 (1.00) | IDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233480-B1 | Chemical compounds | ASTRAZENECA AB (SE) | 2013-05-29 | — | — | EP | claimed |
| EP-2086939-B1 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2010-07-28 | — | — | EP | claimed |