Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3363614 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL28200041 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL3363048 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL25259916 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL2206823 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL25252655 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL17317381 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL31028773 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL3363045 | 1.00 | CYP2A6 (0.44) | CYP2A6TDP1L3MBTL1KCNH2LMNA | |
| Bromide SCHEMBL27618632 | 0.98 | CYP2A6 (0.43) | CYP2A6TDP1L3MBTL1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1009 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486699-A | Spherical particles of clay-based antimicrobial particles | 联合利华知识产权控股有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119421688-A | Particles of clay-based antimicrobial particles | 联合利华知识产权控股有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-115701972-A | Compositions comprising zinc and an antimicrobial agent | 联合利华知识产权控股有限公司 | 2023-02-14 | — | — | CN | claimed |
| CN-110997071-B | Method for promoting tooth remineralization | 联合利华知识产权控股有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-111093775-B | Method for controlling staining of teeth by cationic antimicrobial agents | 联合利华知识产权控股有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-112515987-A | Oral care compositions with adducts of clay and antibacterial agent | 荷兰联合利华有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-111093775-A | Method for controlling staining of teeth due to cationic antimicrobial agents | 荷兰联合利华有限公司 | 2020-05-01 | — | — | CN | claimed |
| CN-110997071-A | Method for promoting tooth remineralization | 荷兰联合利华有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-101750274-B | Differential blood count reagent, kit and method of differential blood count | SHENZHEN MINDRAY BIO MED ELECT | 2014-06-25 | — | — | CN | claimed |
| US-20140154342-A1 | SANDALWOOD OIL AND ITS USES RELATED TO SKIN DISORDERS | SANTALIS PHARMACEUTICALS INC. (US) | 2014-06-05 | — | — | US | claimed |
| CN-1875091-A | Composition with reduced bar wear | COLGATE PALMOLIVE CO (US) | 2006-12-06 | — | — | CN | claimed |
| US-20060024365-A1 | Novel dosage form | VAYA NAVIN | 2006-02-02 | — | — | US | claimed |
| US-20060018933-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| US-20060018934-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| US-5344738-A | Process of making toner compositions | XEROX CORPORATION (US) | 1994-09-06 | — | — | US | claimed |
| EP-0034126-B1 | COSMETIC AND DERMATOLOGICAL COMPOSITIONS FOR SHAVING THE SKIN | Maggesi, Luigi (IT) | 1984-07-04 | — | — | EP | claimed |
| US-4322323-A | Erodible device comprising surfactant for modifying the rate of erosion of the device | ALZA CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| EP-0034126-A1 | Cosmetic and dermatological compositions for shaving the skin | Maggesi, Luigi (IT) | 1981-08-19 | — | — | EP | claimed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| US-3954630-A | QUATERNARY AMMONIUM CATIONIC SOFTENER, POLYCARBOXYLIC ACID COMPLEXING AGENT | COLGATE-PALMOLIVE COMPANY (US) | 1976-05-04 | — | — | US | claimed |