Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.41 |
| ▸ | APAF1 | O14727 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28279990 | 0.98 | IDO1 (0.40) | IDO1APAF1L3MBTL1PPP1CACDC25B | |
| SCHEMBL2538331 | 0.65 | IDO1 (0.38) | IDO1APAF1L3MBTL1PPP1CACDC25B | |
| SCHEMBL6460752 | 0.65 | IDO1 (0.40) | IDO1APAF1L3MBTL1PPP1CACDC25B | |
| SCHEMBL318269 | 0.64 | MEN1 (0.36) | IDO1APAF1L3MBTL1PPP1CACDC25B | |
| SCHEMBL5331883 | 0.62 | IDO1 (0.40) | IDO1APAF1L3MBTL1PPP1CACDC25B | |
| Naphthoquinone SCHEMBL10908172 | 0.61 | IDO1 (0.93) | IDO1APAF1L3MBTL1CDC25BMAOA | |
| Anthraquinone SCHEMBL10905960 | 0.59 | MEN1 (0.92) | IDO1APAF1CDC25BMAOAMAOB | |
| SCHEMBL9302191 | 0.59 | CYP1A2 (0.41) | IDO1APAF1L3MBTL1PPP1CACDC25B | |
| Naphthoquinone SCHEMBL11359780 | 0.57 | IDO1 (1.00) | IDO1APAF1L3MBTL1CDC25BMAOA | |
| Naphthoquinone SCHEMBL29354680 | 0.57 | IDO1 (1.00) | IDO1APAF1L3MBTL1CDC25BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111850101-A | Visual distinguishing method for single-cell DNA epigenetic modification space positioning and adjacent distribution | 西安交通大学 | 2020-10-30 | — | — | CN | claimed |
| EP-1401449-A1 | TETRACYCLIC COMPOUNDS AS PDE5-INHIBITORS | Lilly Icos LLC (US) | 2004-03-31 | — | — | EP | claimed |
| WO-2002098428-A1 | TETRACYCLIC COMPOUNDS AS PDE5-INHIBITORS | LILLY ICOS LLC (US) | 2002-12-12 | — | — | WO | claimed |
| WO-2024017372-A1 | INDOLONE DERIVATIVE AND USE THEREOF | 成都百裕制药股份有限公司 | 2024-01-25 | — | — | WO | disclosed |
| CN-117295523-A | PXR-targeted difunctional PROTAC compound, preparation method and therapeutic application thereof | 国家科学研究中心 | 2023-12-26 | — | — | CN | disclosed |
| WO-2023186069-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-116783179-A | Compounds and methods for targeted degradation of androgen receptor proteins | 阿尔维纳斯运营股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-115776887-A | MDM2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115666575-A | Compound and use thereof | 福宏治疗公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667243-A | Tetrahydroisoquinoline compounds as NRF2 activators | 希四克斯探索有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115605488-A | Bifunctional degradants of hematopoietic progenitor kinases and therapeutic uses thereof | 新锐思生物制药股份有限公司（US） | 2023-01-13 | — | — | CN | disclosed |
| WO-2008115516-A2 | 4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008101824-A1 | IMIDAZO[1',5':1,6] PYRIDO[3,4-B]INDOLES DERIVATIVES AND THERAPEUTICAL USE THEREOF | FOURTILLAN (FR) | 2008-08-28 | — | — | WO | disclosed |
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |
| EP-1401449-A1 | TETRACYCLIC COMPOUNDS AS PDE5-INHIBITORS | Lilly Icos LLC (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-1397361-A1 | CARBOLINE DERIVATIVES AS PDEV INHIBITORS | Lilly Icos LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000691-A1 | CARBOLINE DERIVATIVES AS PDEV INHIBITORS | LILLY ICOS LLC (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002098428-A1 | TETRACYCLIC COMPOUNDS AS PDE5-INHIBITORS | LILLY ICOS LLC (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-0895127-A2 | Photoresist composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-02-03 | — | — | EP | disclosed |