Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.40 |
| ▸ | APAF1 | O14727 | 3/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536229 | 0.65 | MAOA (0.39) | MEN1KMT2AMAOACES1NPC1 | |
| SCHEMBL3244236 | 0.62 | IDO1 (0.41) | IDO1APAF1PPP1CAL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL28279990 | 0.61 | IDO1 (0.40) | IDO1APAF1PPP1CAL3MBTL1MEN1 | |
| SCHEMBL2095985 | 0.59 | KMT2A (0.50) | IDO1APAF1L3MBTL1MEN1KMT2A | |
| 9,10-Phenanthrenequinone SCHEMBL29384320 | 0.58 | MEN1 (1.00) | IDO1APAF1L3MBTL1MEN1KMT2A | |
| 9,10-Phenanthrenequinone SCHEMBL2157215 | 0.58 | MEN1 (1.00) | IDO1APAF1L3MBTL1MEN1KMT2A | |
| Anthraquinone SCHEMBL27722992 | 0.58 | MEN1 (0.92) | IDO1APAF1MEN1KMT2AMAOA | |
| 9,10-Phenanthrenequinone SCHEMBL43050 | 0.58 | MEN1 (1.00) | IDO1APAF1L3MBTL1MEN1KMT2A | |
| 9,10-Phenanthrenequinone SCHEMBL31598775 | 0.58 | MEN1 (1.00) | IDO1APAF1L3MBTL1MEN1KMT2A | |
| SCHEMBL9302191 | 0.57 | CYP1A2 (0.41) | IDO1APAF1PPP1CAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023602-B2 | Hamamelitannin analogues and uses thereof | UNIVERSITEIT GENT (BE) | 2018-07-17 | — | — | US | disclosed |
| EP-3166955-B1 | HAMAMELITANNIN ANALOGUES AND USES THEREOF | UNIV GENT (BE) | 2018-05-02 | — | — | EP | disclosed |
| US-20170158727-A1 | HAMAMELITANNIN ANALOGUES AND USES THEREOF | UNIVERSITEIT GENT (BE) | 2017-06-08 | — | — | US | disclosed |
| JP-2007001911-A | OPTICALLY RECORDING MEDIUM AND 2-(3H-INDOL-2-YL)-1,3-DIONE DERIVATIVE | MITSUI CHEMICALS INC | 2007-01-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023602-B2 | Hamamelitannin analogues and uses thereof | PIGS, HAMP, HTT | IDO1 1059/4885APAF1 3492/4885PPP1CA 1551/4885 |
| US-20170158727-A1 | HAMAMELITANNIN ANALOGUES AND USES THEREOF | PIGS, HAMP, HTT | IDO1 1059/4885APAF1 3492/4885PPP1CA 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.