SCHEMBL3244334

SCHEMBL3244334

CCc1cc(C=O)cc2c1[nH]c1ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.55
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
AHR P35869 1/20 0.49
PIM1 P11309 2/20 0.46
PIM3 Q86V86 2/20 0.46
PIM2 Q9P1W9 1/20 0.46
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218441 0.90 KIF11 (0.51) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL10584704 0.89 KIF11 (0.45) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL28507484 0.88 KIF11 (0.49) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL5399915 0.86 KIF11 (0.48) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL28106992 0.86 KIF11 (0.53) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL8012023 0.85 KIF11 (0.53) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL8003441 0.85 KIF11 (0.53) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL8000392 0.85 KIF11 (0.53) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL5657947 0.85 KIF11 (0.53) KIF11MAPTMEN1KMT2AKDM4E
SCHEMBL28184725 0.85 KIF11 (0.53) KIF11MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776394-A A kind of carbazole derivates and preparation method thereof and preparation H2The application of S donor 朱晓琴 2019-05-21 CN claimed
CN-109608402-A A kind of imidazole derivative ionized compound and preparation method thereof 浙江工业大学 2019-04-12 CN claimed
CN-109232379-A A kind of enhanced fluorescence probe for detecting CN- and preparation method thereof and biologic applications 山西大学 2019-01-18 CN claimed
CN-108383774-A It is a kind of based on the cysteine fluorescence probe of end group acetylenic ketone and its preparation and application 郑州大学 2018-08-10 CN claimed
CN-105203512-B A kind of carbazoles fluorescence probe and its preparation method and application 山西大学 2018-02-06 CN claimed
CN-104628756-B 2, 2-difluoro-4, 6-di (N-ethyl carbazole-3) -2H-1, 3, 2-dioxin borane compound and preparation method and application thereof 中国科学院理化技术研究所 2017-05-17 CN claimed
EP-1432388-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1200051-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
WO-2001013866-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-01 WO claimed
EP-4291951-A1 TWO-COMPONENT SYSTEM Xetos AG (DE) 2023-12-20 EP disclosed
CN-110383173-A Resist lower membrane forms with composition, resist lower membrane and forming method thereof and is formed the manufacturing method of figuratum substrate JSR株式会社 2019-10-25 CN disclosed
CN-105745574-B The preparation of product with conductive microwires figure 伊斯曼柯达公司 2019-09-06 CN disclosed
CN-109988268-A A kind of copolymerization and macromolecular photoinitiator and preparation method thereof 北京化工大学 2019-07-09 CN disclosed
CN-109776394-A A kind of carbazole derivates and preparation method thereof and preparation H2The application of S donor 朱晓琴 2019-05-21 CN disclosed
EP-1473599-A1 Organophotoreceptors with azine-based compounds Samsung Electronics Co., Ltd. (KR) 2004-11-03 EP disclosed
WO-2004058202-A1 DYE TABLETS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-15 WO disclosed
WO-2004031164-A1 HAIR DYES COMPRISING M-PHENYLENEDIAMINE DERIVATIVES AS COUPLING COMPONENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-04-15 WO disclosed
EP-0818431-A1 Scavenger assisted combinatorial process for preparing libaries of secondary amine compounds ELI LILLY AND COMPANY (US) 1998-01-14 EP disclosed
EP-0816310-A2 Scavenger assisted combinatorial process for preparing libraries of tertiary amine compounds ELI LILLY AND COMPANY (US) 1998-01-07 EP disclosed