⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432405 | 0.67 | — | — | |
| SCHEMBL15878918 | 0.65 | — | — | |
| SCHEMBL141108 | 0.64 | — | — | |
| Water SCHEMBL16146969 | 0.64 | — | — | |
| SCHEMBL5368342 | 0.63 | — | — | |
| SCHEMBL11100972 | 0.61 | — | — | |
| SCHEMBL7523798 | 0.59 | — | — | |
| Methylene Chloride SCHEMBL7701261 | 0.59 | CYP3A4 (0.35) | — | |
| Hydrochloric Acid SCHEMBL11412159 | 0.59 | — | — | |
| SCHEMBL1344356 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896488-B1 | PROCESS FOR PURIFYING TACROLIMUS | TEVA GYOGYSZERGYAR ZARTKOERUEE (HU) | 2010-05-19 | — | — | EP | disclosed |
| EP-1896488-A2 | PROCESS FOR PURIFYING TACROLIMUS | TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság (HU) | 2008-03-12 | — | — | EP | disclosed |
| US-20080000834-A1 | Process for purifying Tacrolimus | TEVA GYOGYSZERYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2008-01-03 | — | — | US | disclosed |
| WO-2007106587-A9 | PROCESS FOR PURIFYING TACROLIMUS | TEVA GYOGYSZERGYAR ZARTKORUEN (HU) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007106587-A2 | PROCESS FOR PURIFYING TACROLIMUS | TEVA GYOGYSZERGYAR ZARTKÖRUEN MUKÖDO RESZVENYTARSASAG (HU) | 2007-09-20 | — | — | WO | disclosed |