SCHEMBL5368342

SCHEMBL5368342

[SiH3]C(Cl)(Cl)C(Cl)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5054730 0.71
SCHEMBL15878918 0.71
SCHEMBL1720306 0.69
SCHEMBL12712929 0.65
SCHEMBL3792802 0.63
SCHEMBL3244348 0.63
SCHEMBL17966558 0.63
SCHEMBL8841110 0.60
SCHEMBL1038821 0.58
SCHEMBL9073653 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220703-B2 Tethered polymer ligands HAMMEN CORPORATION (US) 2007-05-22 US disclosed
US-20040224843-A1 Tethered polymer ligands HAMMEN RICHARD F (US) 2004-11-11 US disclosed
US-6689715-B1 Tethered polymer ligands HAMMEN CORPORATION 2004-02-10 US disclosed
US-6251278-B1 CAN BE USED FOR THE SEPARATION AND/OR DETECTION OF BIOLOGICAL AND OTHER MATERIALS BY WAY OF HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY (HPAC) OR OTHER SEPARATION OR DETECTION TECHNIQUES. CHROMATOCHEM, INC. 2001-06-26 US disclosed
EP-0295073-B1 Chromatographic material CHROMATOCHEM INC (US) 1997-03-12 EP disclosed
US-5240602-A Silica solid-support-polyethylene glycol binder-hydrophilic spacer activated coupler ligand CHROMATOCHEM, INC. (US) 1993-08-31 US disclosed
EP-0295073-A2 Chromatographic material CHROMATOCHEM, INC. (US) 1988-12-14 EP disclosed