Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.55 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.50 |
| ▸ | PRKACA | P17612 | 5/20 | 0.49 |
| ▸ | PRKACG | P22612 | 5/20 | 0.49 |
| ▸ | PRKACB | P22694 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247262 | 0.88 | ROCK2 (0.51) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3240430 | 0.88 | ROCK2 (0.61) | ROCK2ROCK1CDC42BPAPRKACAPRKACG | |
| SCHEMBL3247257 | 0.87 | ROCK2 (0.56) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3249977 | 0.86 | ROCK2 (0.75) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3250349 | 0.86 | ROCK2 (0.63) | ROCK2ROCK1CDC42BPAPRKACAPRKACG | |
| SCHEMBL3245171 | 0.84 | ROCK2 (0.69) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3241175 | 0.83 | ROCK2 (0.68) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3245457 | 0.83 | ROCK2 (0.68) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3252837 | 0.83 | ROCK2 (0.64) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3247919 | 0.82 | ROCK2 (0.67) | ROCK2ROCK1PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |