Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674934 | 0.83 | MAOB (0.47) | MAOBMAOAALDH1A1ADORA2BMAPT | |
| SCHEMBL23320363 | 0.81 | MAOB (0.51) | MAOBMAOAALDH1A1ADORA2BMAPT | |
| SCHEMBL6119708 | 0.81 | HPGD (0.47) | MAOBMAOAALDH1A1ADORA2BMAPT | |
| SCHEMBL1299217 | 0.79 | MAOB (0.58) | MAOBMAOAALDH1A1ADORA2BMAPT | |
| SCHEMBL5158448 | 0.79 | MAOB (0.49) | MAOBPSMB5MAOAADORA2BMAPT | |
| SCHEMBL8761733 | 0.79 | MAOB (0.61) | MAOBMAOAADORA2BMAPTNPC1 | |
| SCHEMBL28856330 | 0.79 | GAA (0.74) | MAOBMAOAALDH1A1MAPTGAA | |
| SCHEMBL11884086 | 0.78 | MAOB (0.66) | MAOBMAOAADORA2BKMT2A | |
| SCHEMBL70456 | 0.77 | MAOB (0.76) | MAOBMAOAALDH1A1ADORA2BMAPT | |
| SCHEMBL6835355 | 0.77 | ALDH1A1 (0.55) | MAOBALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106604919-B | Crystal form of 6- ((6, 7-dimethoxyquinazolin-4-yl) oxy) -N, 2-dimethylbenzofuran-3-carboxamide | 和记黄埔医药（上海）有限公司 | 2019-11-15 | — | — | CN | disclosed |
| CN-106604919-A | Crystal form of 6- ((6, 7-dimethoxyquinazolin-4-yl) oxy) -N, 2-dimethylbenzofuran-3-carboxamide | 和记黄埔医药（上海）有限公司 | 2017-04-26 | — | — | CN | disclosed |
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |
| WO-2010025138-A2 | PYRIMIDINE COMPOUNDS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2010-03-04 | — | — | WO | disclosed |