Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245506 | 1.00 | LMNA (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| SCHEMBL3244781 | 1.00 | LMNA (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL3249873 | 0.99 | LMNA (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL3250783 | 0.99 | LMNA (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL3249868 | 0.99 | LMNA (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| SCHEMBL13928170 | 0.88 | MAPT (0.36) | LMNATP53MAPTKDM4EHPGD | |
| SCHEMBL13928169 | 0.88 | MAPT (0.36) | LMNATP53MAPTKDM4EHPGD | |
| SCHEMBL3251058 | 0.88 | MAPT (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| SCHEMBL3251059 | 0.88 | MAPT (0.37) | LMNATP53MAPTPRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL3254764 | 0.87 | MAPT (0.36) | LMNATP53MAPTPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | disclosed |