Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28151662 | 1.00 | FFAR3 (0.50) | FFAR3LCKFYNLMNATDP1 | |
| Acetic Acid SCHEMBL4600958 | 1.00 | FFAR3 (0.50) | FFAR3LCKFYNLMNATDP1 | |
| Acetic Acid SCHEMBL1307878 | 0.96 | — | — | |
| Acetic Acid SCHEMBL28307524 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNATDP1 | |
| Acetic Acid SCHEMBL1791343 | 0.96 | — | — | |
| Acetic Acid SCHEMBL217277 | 0.96 | — | — | |
| Acetic Acid SCHEMBL544816 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNATDP1 | |
| Acetic Acid SCHEMBL4014382 | 0.93 | FFAR3 (0.58) | FFAR3LCKFYNLMNATDP1 | |
| Acetic Acid SCHEMBL15658788 | 0.93 | FFAR3 (0.58) | FFAR3LCKFYNLMNATDP1 | |
| Acetic Acid SCHEMBL4986972 | 0.93 | FFAR3 (0.58) | FFAR3LCKFYNLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106872589-B | A kind of detection method of the right phenyl ethylamine salt of left phosphonomycin and its enantiomter | 江苏开元医药化工有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-106872589-B | A kind of detection method of the right phenyl ethylamine salt of left phosphonomycin and its enantiomter | 江苏开元医药化工有限公司 | 2019-04-02 | — | — | CN | disclosed |
| US-9468602-B2 | Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules | AZAD PHARMA AG (CH) | 2016-10-18 | — | — | US | disclosed |
| CN-104771595-A | Chinese medicinal composition for enhancing immunity and preparation method thereof | GUANGXI LONGFENGSHAN BIOTECHNOLOGY CO LTD | 2015-07-15 | — | — | CN | disclosed |
| EP-2606877-A1 | Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules | Azad Pharma AG (CH) | 2013-06-26 | — | — | EP | disclosed |
| EP-2384188-B1 | PHARMACEUTICAL MICROEMULSION FOR PREVENTING SUPRAMOLECULAR AGGREGATION OF AMPHIPHILIC MOLECULES | AZAD PHARMA AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| CN-101444604-B | Chinese medicine granule to treat children anorexia and preparation method thereof and detection method | GUIZHOU BENCAOTANG PHARMACEUTICAL CO LTD | 2012-01-11 | — | — | CN | disclosed |
| EP-2204167-A1 | Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules | Azad Pharma AG (CH) | 2010-07-07 | — | — | EP | disclosed |
| CN-101444604-A | Chinese medicine granular formulation to therapy children anorexia and preparation method thereof and detection method | GUIZHOU BENCAOTANG PHARMACEUTI (CN) | 2009-06-03 | — | — | CN | disclosed |
| CN-101428107-A | Process for producing osmanthus attached glutinous rehmannia formulation | XIONGHUI ZENG (CN) | 2009-05-13 | — | — | CN | disclosed |
| CN-101347470-A | Glossy privet fruit total triterpenes extract and total phenols extract as well as preparation method thereof | RENBING SHI (CN) | 2009-01-21 | — | — | CN | disclosed |