Acetic Acid

Acetic Acid

SCHEMBL544816

CC#N.CC(=O)O.CO.O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.54
LCK P06239 1/20 0.54
FYN P06241 1/20 0.54
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
THPO P40225 1/20 0.33
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1791343 1.00
Acetic Acid SCHEMBL4600958 0.96 FFAR3 (0.50) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL3244968 0.96 FFAR3 (0.50) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL28151662 0.96 FFAR3 (0.50) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL15658788 0.96 FFAR3 (0.58) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL4986972 0.96 FFAR3 (0.58) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL211103 0.96
Acetic Acid SCHEMBL11256435 0.96 FFAR3 (0.58) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL16004804 0.96 FFAR3 (0.58) FFAR3LCKFYNLMNATDP1
Acetic Acid SCHEMBL15657988 0.96 FFAR3 (0.58) FFAR3LCKFYNLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111606815-B Preparation method of phenylephrine hydrochloride impurity standard 珠海安哲生物科技有限公司 2022-02-11 CN claimed
CN-111606815-A Preparation method of phenylephrine hydrochloride impurity standard 珠海安哲生物科技有限公司 2020-09-01 CN claimed
CN-101703583-B Quality detection method of Xinning capsules GUIYANG XIN TIAN PHARMACEUTICAL CO LTD 2012-05-30 CN claimed
CN-101703583-A Method for detecting quality of Xinning capsule GUIYANG XIN TIAN PHARMACEUTICA 2010-05-12 CN claimed
CN-117214336-A Method for detecting epipiprazole, intermediate and impurity 湖南省湘中制药有限公司 2023-12-12 CN disclosed
CN-116256438-A Analysis and detection method for beraprost sodium intermediate III isomer 重庆药友制药有限责任公司 2023-06-13 CN disclosed
US-11534494-B2 Formulation and method of synthesis GE HEALTHCARE LIMITED (GB) 2022-12-27 US disclosed
US-11297863-B2 Emulsified seasoning KAO CORPORATION (JP) 2022-04-12 US disclosed
WO-2022034226-A1 AVERMECTIN AND MILBEMYCIN COMPOSITIONS FOR INHALATION UNIVERSIDAD DE NAVARRA (ES) 2022-02-17 WO disclosed
CN-111606815-B Preparation method of phenylephrine hydrochloride impurity standard 珠海安哲生物科技有限公司 2022-02-11 CN disclosed
US-20220001034-A1 NOVEL FORMULATION AND METHOD OF SYNTHESIS GE HEALTHCARE LTD (GB) 2022-01-06 US disclosed
US-11206858-B2 Separated liquid seasoning KAO CORPORATION (JP) 2021-12-28 US disclosed
US-20090023596-A1 In Vitro Model Of Latent Mycobacterial Infection NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-01-22 US disclosed
WO-2008134298-A1 IN VITRO MODEL OF LATENT MYCOBACTERIAL INFECTION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-11-06 WO disclosed
US-20080248155-A1 Use of Stevensite For Mycotoxin Adsorption SUD-CHEMIE AG (DE) 2008-10-09 US disclosed
CN-101241114-A Animal source food sulfonamide residual medium solid phase dispersion-highly effective liquid phase chromatography determination method BEIJING GLORIOUS LAND AGRICULT (CN) 2008-08-13 CN disclosed
US-6613539-B1 Use as a mass screening technique to measure the biological activity of large quantities of compounds using an orthogonal array method WARNER LAMBERT COMPANY 2003-09-02 US disclosed
US-6204034-B1 ENZYME WITH DEFINED PARTIAL AMINO-TERMINAL AMINO ACID SEQUENCE; ENZYME INHIBITORS; ANTIBODIES; ANTIINFLAMMATORY AGENTS MERCK FROSST CANADA & CO. (CA) 2001-03-20 US disclosed
WO-1993025668-A1 LEUKOTRIENE C4 SYNTHASE MERCK FROSST CANADA INC. (CA) 1993-12-23 WO disclosed
US-4835707-A Automatic analysis method and apparatus for enzyme reaction TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11534494-B2 Formulation and method of synthesis PFAS, ARF5, FAU FFAR3 341/4885LCK 3026/4885FYN 1379/4885
US-20220001034-A1 NOVEL FORMULATION AND METHOD OF SYNTHESIS AFF1, PAICS, FOLR1 FFAR3 25/4885LCK 4078/4885FYN 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.