Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064818 | 0.85 | EPHX1 (0.66) | MARS1EPHX1ALDH1A1CYP1A2HTT | |
| SCHEMBL8601252 | 0.82 | EPHX1 (0.75) | MARS1EPHX1ALDH1A1HTTMAPT | |
| SCHEMBL8599247 | 0.82 | EPHX1 (0.75) | MARS1EPHX1ALDH1A1HTTMAPT | |
| SCHEMBL3157400 | 0.82 | EPHX1 (0.75) | MARS1EPHX1ALDH1A1HTTMAPT | |
| SCHEMBL8598231 | 0.82 | EPHX1 (0.75) | MARS1EPHX1ALDH1A1HTTMAPT | |
| SCHEMBL8599536 | 0.82 | EPHX1 (0.75) | MARS1EPHX1ALDH1A1HTTMAPT | |
| SCHEMBL4063235 | 0.82 | EPHX1 (0.68) | EPHX1ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL7098401 | 0.82 | MARS1 (0.55) | MARS1EPHX1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL28516814 | 0.81 | MAPT (0.72) | MARS1EPHX1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL6688583 | 0.81 | MARS1 (0.60) | MARS1EPHX1ALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| EP-1136886-B1 | Positive-working presensitized plate useful for preparing a lithographic printing plate | FUJIFILM CORP (JP) | 2010-05-19 | — | — | EP | disclosed |