Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247125 | 0.92 | CNR2 (0.41) | ALDH1A1SLC22A12LMNATP53MAPT | |
| SCHEMBL3245321 | 0.91 | CNR2 (0.45) | SLC22A12LMNATP53MAPTPOLB | |
| SCHEMBL3241599 | 0.90 | SLC22A12 (0.40) | ALDH1A1SLC22A12SMN1; SMN2LMNATP53 | |
| SCHEMBL3241859 | 0.90 | SLC22A12 (0.40) | ALDH1A1SLC22A12LMNATP53MAPT | |
| SCHEMBL3245291 | 0.90 | SLC22A12 (0.40) | ALDH1A1SLC22A12LMNATP53MAPT | |
| SCHEMBL3239774 | 0.90 | LMNA (0.46) | ALDH1A1SLC22A12SMN1; SMN2LMNATP53 | |
| SCHEMBL3246470 | 0.90 | SLC22A12 (0.41) | ALDH1A1SLC22A12LMNATP53MAPT | |
| SCHEMBL3241579 | 0.90 | SLC22A12 (0.38) | ALDH1A1SLC22A12SMN1; SMN2LMNATP53 | |
| SCHEMBL3239637 | 0.89 | SLC22A12 (0.39) | ALDH1A1SLC22A12LMNATP53MAPT | |
| SCHEMBL3241585 | 0.89 | SLC22A12 (0.39) | ALDH1A1SLC22A12LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |