Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 1.00 |
| ▸ | PI4KA | P42356 | 4/20 | 1.00 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 1.00 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.97 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.97 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.91 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | THPO | P40225 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978424 | 0.98 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21435666 | 0.95 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28984637 | 0.92 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| Methyl Alcohol SCHEMBL10438261 | 0.91 | ADORA2A (0.91) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20536490 | 0.87 | CYP1A2 (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3712758 | 0.84 | ADORA2A (0.79) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| Hydrochloric Acid SCHEMBL15310347 | 0.83 | ADORA2A (0.77) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17546014 | 0.83 | ADORA2A (0.72) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6467183 | 0.81 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11400740 | 0.81 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-7365178-B2 | Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis | ACTIVX BIOSCIENCES, INC. (US) | 2008-04-29 | — | — | US | claimed |
| US-20050043507-A1 | Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis | ACTIVX BIOSCIENCES, INC. | 2005-02-24 | — | — | US | claimed |
| US-4278675-A | ADMINISTERING 9-CYCLOHEXYL-9H-ADENINE OR 9-BENZYL-2-N-PROPOXY-9H-ADENINE | BRISTOL-MYERS COMPANY (US) | 1981-07-14 | — | — | US | claimed |
| CN-119546750-A | Methods for making and using differentiated neural cells | 研究发展基金会 | 2025-02-28 | — | — | CN | disclosed |
| CN-116492347-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022187839-A1 | COMBINATION THERAPY TO TREAT TEMPERATURE SENSTIVE MUTANT TUMORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (US) | 2022-09-09 | — | — | WO | disclosed |
| CN-113827657-A | Traditional Chinese medicine composition preparation for treating epidemic cold (qi-yin deficiency syndrome) and application | 云南省中医医院(云南中医药大学第一附属医院) | 2021-12-24 | — | — | CN | disclosed |
| CN-111544498-A | New application of angelica sinensis and peony powder | 天津中医药大学 | 2020-08-18 | — | — | CN | disclosed |
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
| CN-108703970-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2018-10-26 | — | — | CN | disclosed |
| US-20050043507-A1 | Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis | ACTIVX BIOSCIENCES, INC. | 2005-02-24 | — | — | US | disclosed |
| WO-2004090154-A2 | ACYL- PHOSPHATE AND PHOSPHONATE PROBES AND METHODS OF THEIR SYNTHESIS AND USE IN PROTEOMIC ANALYSIS | ACTIVX BIOSCIENCES, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| EP-0755255-A4 | TREATMENT OF TOXOPLASMOSIS | RES CORP TECHNOLOGIES INC (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5773424-A | PARASITICIDE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0755255-A1 | TREATMENT OF TOXOPLASMOSIS | UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996018398-A1 | TREATMENT OF TOXOPLASMOSIS | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) | 1996-06-20 | — | — | WO | disclosed |
| US-4278675-A | ADMINISTERING 9-CYCLOHEXYL-9H-ADENINE OR 9-BENZYL-2-N-PROPOXY-9H-ADENINE | BRISTOL-MYERS COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| US-4086347-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS, HYPOTENSIVES | BOEHRINGER MANNHEIM GMBH (DT) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043507-A1 | Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis | GTPBP4, NCBP1, RRBP1 | ADORA2A 2267/4885PI4KA 2884/4885PI4K2B 2791/4885 |
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | ADORA2A 1642/4885PI4KA 1612/4885PI4K2B 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.