Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.61 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245404 | 0.94 | ROCK2 (0.64) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3122305 | 0.89 | ROCK2 (0.73) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3116367 | 0.88 | ROCK2 (0.71) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3241451 | 0.86 | ROCK2 (0.69) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3241106 | 0.85 | ROCK2 (0.68) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3245103 | 0.85 | ROCK2 (0.67) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3242746 | 0.83 | ROCK2 (0.58) | ROCK2ROCK1CDC42BPAKDR | |
| SCHEMBL3245838 | 0.83 | ROCK2 (0.69) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3249358 | 0.82 | ROCK2 (0.56) | ROCK2ROCK1CDC42BPAKDR | |
| SCHEMBL3253118 | 0.81 | ROCK2 (0.64) | ROCK2ROCK1CDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |