Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 3/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28323653 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL9066054 | 0.98 | ALDH1A1 (0.36) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL2971818 | 0.98 | ALDH1A1 (0.36) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL2793471 | 0.98 | ALDH1A1 (0.36) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL27092915 | 0.98 | ALDH1A1 (0.36) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL12500512 | 0.98 | ALDH1A1 (0.36) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL3245946 | 0.94 | HCAR2 (0.41) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL5177120 | 0.84 | ALDH1A1 (0.36) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| Maleic Acid SCHEMBL8324326 | 0.83 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL9878914 | 0.83 | ALDH1A1 (0.35) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017017677-A1 | COMBINATION TREATMENT FOR LIVER DISEASE | GALMED RESEARCH AND DEVELOPMENT LTD. (IL) | 2017-02-02 | — | — | WO | claimed |
| US-9072693-B2 | Micronutrient supplement with calcium, vitamin D or calcium and vitamin D combination for premenstrual/menstrual relief | THYS-JACOBS SUSAN (US) | 2015-07-07 | — | — | US | claimed |
| EP-1753403-B1 | PARTICULATE COMPRISING A CALCIUM-CONTAINING COMPOUND AND A SUGAR ALCOHOL | TAKEDA NYCOMED AS (NO) | 2014-08-13 | — | — | EP | claimed |
| EP-1962807-B1 | FILM-COATED AND/OR GRANULATED CALCIUM-CONTAINING COMPOUNDS AND USE THEREOF IN PHARMACEUTICAL COMPOSITIONS | TAKEDA NYCOMED AS (NO) | 2014-08-06 | — | — | EP | claimed |
| EP-2436378-B1 | Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions | TAKEDA NYCOMED AS (NO) | 2014-08-06 | — | — | EP | claimed |
| US-20120195981-A1 | MICRONUTRIENT SUPPLEMENT WITH CALCIUM, VITAMIN D OR CALCIUM & VITAMIN D COMBINATION FOR PREMENSTRUAL SYNDROME, POSTPARTUM DEPRESSION, DEPRESSION AND PANIC ATTACKS | THYS-JACOBS SUSAN (US) | 2012-08-02 | — | — | US | claimed |
| US-20090263508-A1 | MICRONUTRIENT SUPPLEMENT WITH CALCIUM, VITAMIN D OR CALCIUM & VITAMIN D COMBINATION FOR PREMENSTRUAL SYNDROME, POSTPARTUM DEPRESSION, DEPRESSION AND PANIC ATTACKS | THYS-JACOBS SUSAN | 2009-10-22 | — | — | US | claimed |
| US-20070098819-A1 | Micronutrient supplement with calcium, vitamin D or calcium & vitamin D combination for premenstrual syndrome, postpartum depression, depression and panic attacks | THYS-JACOBS SUSAN | 2007-05-03 | — | — | US | claimed |
| WO-2017017677-A1 | COMBINATION TREATMENT FOR LIVER DISEASE | GALMED RESEARCH AND DEVELOPMENT LTD. (IL) | 2017-02-02 | — | — | WO | disclosed |
| US-9072693-B2 | Micronutrient supplement with calcium, vitamin D or calcium and vitamin D combination for premenstrual/menstrual relief | THYS-JACOBS SUSAN (US) | 2015-07-07 | — | — | US | disclosed |
| US-9072693-B2 | Micronutrient supplement with calcium, vitamin D or calcium and vitamin D combination for premenstrual/menstrual relief | THYS-JACOBS SUSAN (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120195981-A1 | MICRONUTRIENT SUPPLEMENT WITH CALCIUM, VITAMIN D OR CALCIUM & VITAMIN D COMBINATION FOR PREMENSTRUAL SYNDROME, POSTPARTUM DEPRESSION, DEPRESSION AND PANIC ATTACKS | THYS-JACOBS SUSAN (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120195981-A1 | MICRONUTRIENT SUPPLEMENT WITH CALCIUM, VITAMIN D OR CALCIUM & VITAMIN D COMBINATION FOR PREMENSTRUAL SYNDROME, POSTPARTUM DEPRESSION, DEPRESSION AND PANIC ATTACKS | THYS-JACOBS SUSAN (US) | 2012-08-02 | — | — | US | disclosed |
| US-7807641-B2 | Methods and reagents for treating glucose metabolic disorders | CURIS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20070098819-A1 | Micronutrient supplement with calcium, vitamin D or calcium & vitamin D combination for premenstrual syndrome, postpartum depression, depression and panic attacks | THYS-JACOBS SUSAN | 2007-05-03 | — | — | US | disclosed |
| US-20070098819-A1 | Micronutrient supplement with calcium, vitamin D or calcium & vitamin D combination for premenstrual syndrome, postpartum depression, depression and panic attacks | THYS-JACOBS SUSAN | 2007-05-03 | — | — | US | disclosed |
| US-20040228846-A1 | Methods and reagents for treating glucose metabolic disorders | CURIS, INC. | 2004-11-18 | — | — | US | disclosed |
| US-6558690-B2 | To be administered concurrently with the lipase inhibitor to negate the action of the latter in inhibiting the release of cholecystokinin (CCK) which, in turn, reduces the feeling of satiety and stimulates appetite | PACIFIC HEALTH LABORATORIES, INC. | 2003-05-06 | — | — | US | disclosed |
| US-20020110580-A1 | Nutritional composition for improving the efficacy of a lipase inhibitor | ANAYA PERSONAL CARE PRODUCTS LLC | 2002-08-15 | — | — | US | disclosed |
| WO-2002047614-A2 | NUTRITIONAL COMPOSITION FOR IMPROVING THE EFFICACY OF A LIPASE INHIBITOR | PACIFIC HEALTH LABORATORIES, INC. (US) | 2002-06-20 | — | — | WO | disclosed |