SCHEMBL3246183

SCHEMBL3246183

NCCCOCCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.59
HTR2A P28223 2/20 0.54
CYP2A6 P11509 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.54
IDO1 P14902 1/20 0.50
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SIGMAR1 Q99720 2/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19472539 0.94 MAOA (0.63) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL1579959 0.92 MAOA (0.61) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL3438742 0.92 MAOA (0.65) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
Phenethylamine SCHEMBL7263898 0.92 HTR2A (0.67) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL22268839 0.88 MAOA (0.67) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL22873145 0.88 HTR2A (0.50) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL4726492 0.87 HTR2A (0.58) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL10818930 0.86 MAOA (0.69) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1
SCHEMBL4030630 0.85 MAOB (0.57) MAOASMN1; SMN2
Hydrochloric Acid SCHEMBL29004380 0.85 HTR2A (0.56) MAOAHTR2ACYP2A6SMN1; SMN2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1184364-B1 COMB-SHAPED DIOL, WATER-SOLUBLE POLYURETHANE, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2010-07-28 EP disclosed
US-6515050-B1 An extruding auxiliary using the above novel water-soluble polyurethane; additive for underwater concrete MITSUI CHEMICALS, INC. (JP) 2003-02-04 US disclosed
EP-1184364-A1 COMB-SHAPED DIOL, WATER-SOLUBLE POLYURETHANE, AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2002-03-06 EP disclosed
US-4157893-A MONO OR DISAZO DYE CONTAINING AN AMINO-SUBSTITUTED PYRIMIDINE RING BASF AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed