Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238762 | 0.83 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3249556 | 0.83 | ROCK2 (0.70) | ROCK2 | |
| SCHEMBL13391207 | 0.82 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL3249431 | 0.82 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3241041 | 0.81 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3248557 | 0.81 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3240681 | 0.81 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3249722 | 0.81 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3241411 | 0.78 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL3245134 | 0.77 | ROCK2 (0.79) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |