Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 10/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251252 | 0.93 | GAA (0.47) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL3236789 | 0.91 | GAA (0.55) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL13521136 | 0.91 | TSHR (0.56) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL3254471 | 0.89 | TSHR (0.46) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL13521719 | 0.87 | TSHR (0.46) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL3241489 | 0.85 | TSHR (0.46) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL3251960 | 0.85 | TSHR (0.43) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL3241049 | 0.82 | TSHR (0.46) | GAATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL13521687 | 0.82 | GAA (0.39) | GAATSHRMAPK1GRIN2BL3MBTL1 | |
| SCHEMBL13521716 | 0.81 | MEN1 (0.40) | GAATSHRMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |