Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 16/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.40 |
| ▸ | BCL9 | O00512 | 3/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237438 | 0.86 | ROCK2 (0.65) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3125123 | 0.81 | ROCK2 (0.51) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3247906 | 0.79 | ROCK2 (0.65) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3249296 | 0.77 | ROCK2 (0.77) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3248971 | 0.77 | ROCK2 (0.64) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3129341 | 0.77 | ROCK2 (0.65) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3241441 | 0.75 | ROCK2 (0.85) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3245577 | 0.74 | ROCK2 (0.76) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3247086 | 0.74 | ROCK2 (0.73) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3246339 | 0.73 | ROCK2 (0.72) | ROCK2ROCK1CDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |