Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471292 | 0.92 | MAPT (0.56) | MAPTL3MBTL1SRD5A2CES1STS | |
| Water SCHEMBL9243001 | 0.87 | MAPT (0.70) | MAPTL3MBTL1SRD5A2CES1STS | |
| Water SCHEMBL20527670 | 0.87 | MAPT (0.70) | MAPTL3MBTL1SRD5A2CES1STS | |
| SCHEMBL24800 | 0.85 | MAPT (0.73) | MAPTL3MBTL1SRD5A2CES1STS | |
| SCHEMBL7129800 | 0.85 | MAPT (0.80) | MAPTL3MBTL1SRD5A2CES1STS | |
| SCHEMBL4282905 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2CES1STS | |
| Bicarbonate SCHEMBL28984888 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2CES1STS | |
| Hydrochloric Acid SCHEMBL27315608 | 0.83 | MAPT (0.70) | MAPTL3MBTL1SRD5A2CES1STS | |
| Methyl Alcohol SCHEMBL11602292 | 0.81 | MAPT (0.68) | MAPTL3MBTL1SRD5A2CES1STS | |
| Formaldehyde SCHEMBL27372987 | 0.81 | MAPT (0.68) | MAPTL3MBTL1SRD5A2CES1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180267-A | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTV (RU) | 2008-05-14 | — | — | CN | claimed |
| CN-104066735-A | Substituted imidazopyrazines as AKT kinase inhibitors | BAYER IP GMBH | 2014-09-24 | — | — | CN | disclosed |
| CN-101600706-B | Inhibitors of akt activity | MERCK SHARP & DOHME | 2013-10-16 | — | — | CN | disclosed |
| CN-101374515-B | Inhibitors of akt activity | MERCK SHARP & DOHME | 2013-01-09 | — | — | CN | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| CN-101374515-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2009-02-25 | — | — | CN | disclosed |
| CN-101180267-A | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTV (RU) | 2008-05-14 | — | — | CN | disclosed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1354602-B1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | SANKYO CO (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1695716-A2 | Medicinal compositions containing diuretics and insulin sensitizers | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| EP-1167357-A1 | ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6020426-A | BLOCK OR GRAFT COPOLYMER | FUJI XEROX CO., LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| CN-1242007-A | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds | ELAND PHARMACEUTICAL CORP (US) | 2000-01-19 | — | — | CN | disclosed |
| EP-0534257-B1 | Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof | MITSUI TOATSU CHEMICALS (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5306688-A | Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-26 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0534257-A1 | Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-03-31 | — | — | EP | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |