SCHEMBL3249083

SCHEMBL3249083

C1CC[C](CCNC2CCCCC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.48
HRH3 Q9Y5N1 6/20 0.47
TAAR1 Q96RJ0 1/20 0.47
CXCR4 P61073 4/20 0.47
CXCL12 P48061 1/20 0.47
LMNA P02545 1/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HRH4 Q9H3N8 4/20 0.40
RAD52 P43351 1/20 0.40
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1779849 0.77 RAD52 (0.56) DPP7HRH3TAAR1CXCR4CXCL12
SCHEMBL455085 0.77 RAD52 (0.56) DPP7HRH3TAAR1CXCR4CXCL12
SCHEMBL12204005 0.77 SMN1; SMN2 (0.64) HRH3TAAR1KDM4E
SCHEMBL6983120 0.76 HRH3 (0.57) DPP7HRH3CXCR4CXCL12KDM4E
SCHEMBL3298507 0.74 RAD52 (0.52) DPP7HRH3TAAR1CXCR4CXCL12
SCHEMBL18677179 0.72 TAAR1 (0.59) HRH3TAAR1CXCR4CXCL12KDM4E
SCHEMBL5555509 0.72 TAAR1 (0.59) HRH3TAAR1CXCR4CXCL12LMNA
SCHEMBL13773051 0.72 TAAR1 (0.64) HRH3TAAR1CXCR4CXCL12LMNA
SCHEMBL9263068 0.72 CXCR4 (0.66) HRH3TAAR1CXCR4CXCL12LMNA
SCHEMBL9417435 0.72 CXCR4 (0.61) HRH3CXCR4CXCL12KDM4EHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602688-B1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE, AND FILM TORAY INDUSTRIES (JP) 2010-05-19 EP disclosed
US-7462671-B2 Thermoplastic resin composition, molded article, and film TORAY INDUSTRIES, INC. (JP) 2008-12-09 US disclosed
US-20060100391-A1 Thermoplastic resin composition, molded article, and film TORAY INDUSTRIES, INC. (JP) 2006-05-11 US disclosed
EP-1602688-A1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE, AND FILM TORAY INDUSTRIES, INC. (JP) 2005-12-07 EP disclosed