Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 9/20 | 1.00 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 1.00 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255871 | 0.89 | ROCK2 (0.80) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3250523 | 0.88 | ROCK2 (0.81) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3240825 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPAMYLK4 | |
| SCHEMBL3249790 | 0.87 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3242561 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPAMYLK4 | |
| SCHEMBL21507623 | 0.78 | ROCK2 (0.64) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3238860 | 0.76 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPAMYLK4 | |
| SCHEMBL20661172 | 0.76 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL20661117 | 0.75 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL3240681 | 0.75 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |