SCHEMBL3249368

SCHEMBL3249368

C=CC(C=C(CC(CC)CCCC)C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
CA2 P00918 3/20 0.39
MAPK1 P28482 1/20 0.39
GRIK1 P39086 4/20 0.37
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
ATM Q13315 1/20 0.36
GPR84 Q9NQS5 4/20 0.34
GRIA2 P42262 2/20 0.34
GRIA4 P48058 2/20 0.34
GRIK3 Q13003 2/20 0.34
GRIK5 Q16478 2/20 0.34
GRIK2 Q13002 2/20 0.34
FFAR1 O14842 1/20 0.34
GRIA1 P42261 1/20 0.34
RECQL P46063 1/20 0.33
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1602711 0.81 IAPP (0.33) TSHRCA2ALDH1A1TDP1CYP3A4
SCHEMBL294296 0.80 TSHR (0.46) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL7253492 0.79 CA2 (0.46) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL6550732 0.79 CA2 (0.46) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL3673167 0.79 CA2 (0.46) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL4906534 0.78 TSHR (0.39) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL3249505 0.78 GRIK1 (0.39) CA2MAPK1GRIK1ALDH1A1GPR84
SCHEMBL149377 0.78 CA2 (0.44) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL15162943 0.76 GRIK1 (0.50) TSHRCA2MAPK1GRIK1ALDH1A1
SCHEMBL2250221 0.76 CA2 (0.43) TSHRCA2MAPK1GRIK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957549-B1 POLYVINYLESTER SOLID RESINS HAVING HIGH POLYDISPERSITY WACKER CHEMIE AG (DE) 2010-05-19 EP claimed
EP-1957549-A2 POLYVINYLESTER AND POLY(METH)ACRYLATE SOLID RESINS HAVING HIGH POLYDISPERSITY Wacker Polymer Systems GmbH & Co. KG (DE) 2008-08-20 EP claimed
WO-2007065804-A2 POLYVINYLESTER AND POLY(METH)ACRYLATE SOLID RESINS HAVING HIGH POLYDISPERSITY WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2007-06-14 WO claimed
EP-1957549-B1 POLYVINYLESTER SOLID RESINS HAVING HIGH POLYDISPERSITY WACKER CHEMIE AG (DE) 2010-05-19 EP disclosed
EP-1957549-A2 POLYVINYLESTER AND POLY(METH)ACRYLATE SOLID RESINS HAVING HIGH POLYDISPERSITY Wacker Polymer Systems GmbH & Co. KG (DE) 2008-08-20 EP disclosed
WO-2007065804-A2 POLYVINYLESTER AND POLY(METH)ACRYLATE SOLID RESINS HAVING HIGH POLYDISPERSITY WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2007-06-14 WO disclosed
EP-1713522-A1 WOUND DRESSING AND RAPID WOUND DRESSING COMPRISING A VASOCONSTRICTIVE INGREDIENT LTS LOHMANN Therapie-Systeme AG (DE) 2006-10-25 EP disclosed
WO-2005065732-A1 WOUND DRESSING AND RAPID WOUND DRESSING COMPRISING A VASOCONSTRICTIVE INGREDIENT LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2005-07-21 WO disclosed